On behalf of the IronPython team, I'm happy to announce the second beta release of IronPython 2.7.5. This release includes everything from IronPython 2.7.4 and earlier. Like all IronPython 2.7-series releases, .NET 4 is required to install it. Installing this release will replace any existing IronPython 2.7-series installation. Assemblies for embedding are provided for .NET 3.5, .NET 4, .NET 4.5, and Silverlight 5.
IronPython 2.7.5 Beta 2 is primarily a collection of bug fixes which smooths off many of the remaining rough edges. The complete list of changes is also available.
Note: The assembly version of IronPython has changed to 220.127.116.11. All previous 2.7 versions had the same version (18.104.22.168) which caused issues when different versions were installed. Publisher policy files are used to so that applications don't have to be recompiled, but recompiling is strongly recommended.
For Visual Studio integration, check out Python Tools for Visual Studio which has support for IronPython as well as CPython, and many other fantastic features.
IronPython 2.7.5 Beta 2 is also available for embedding via NuGet. The main package is IronPython, and the standard library is in IronPython.StdLib.